HLX

HLX (H2.0 Like Homeobox) is a Protein Coding gene. Diseases associated with HLX include Ovarian Endodermal Sinus Tumor and Ovarian Primitive Germ Cell Tumor. Among its related pathways are IL12-mediated signaling events. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DBX1.

H2.0 like homeobox

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).

Cell differentiation Source: UniProtKB-KW
Embryonic digestive tract morphogenesis Source: Ensembl
Enteric nervous system development Source: Ensembl
Liver development Source: Ensembl
Multicellular organism development Source: ProtInc
Negative regulation of T-helper 2 cell differentiation Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of organ growth Source: Ensembl
Positive regulation of T-helper 1 cell differentiation Source: Ensembl
Skeletal muscle tissue development Source: Ensembl

Nucleus