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Mouse Anti-HLX (AA 176-279) Recombinant Antibody (CBFYH-1486) (CBMAB-H2441-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-1486
Antibody Isotype
IgG2a, κ
Application
ELISA, IP, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: FGIDRILSAE FDPKVKEGNT LRDLTSLLTG GRPAGVHLSG LQPSAGQFFA SLDPINEASA ILSPLNSNPR NSVQHQFQDT FPGPYAVLTK DTMPQTYKRK RSWS
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 176-279

Target

Full Name
H2.0 like homeobox
Introduction
HLX (H2.0 Like Homeobox) is a Protein Coding gene. Diseases associated with HLX include Ovarian Endodermal Sinus Tumor and Ovarian Primitive Germ Cell Tumor. Among its related pathways are IL12-mediated signaling events. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DBX1.
Entrez Gene ID
3142
UniProt ID
Q14774
Alternative Names
H2.0 Like Homeobox; Homeobox Protein HB24; Homeobox Protein HLX1; H2.0-Like Homeobox 1; HLX1; H2.0 (Drosophila)-Like Homeo Box 1
Function
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
Biological Process
Cell differentiation Source: UniProtKB-KW
Embryonic digestive tract morphogenesis Source: Ensembl
Enteric nervous system development Source: Ensembl
Liver development Source: Ensembl
Multicellular organism development Source: ProtInc
Negative regulation of T-helper 2 cell differentiation Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of organ growth Source: Ensembl
Positive regulation of T-helper 1 cell differentiation Source: Ensembl
Skeletal muscle tissue development Source: Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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