HNRNPA0

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. [provided by RefSeq, Jul 2008]
Full Name
Heterogeneous Nuclear Ribonucleoprotein A0
Function
mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs.
Biological Process
3'-UTR-mediated mRNA stabilization Source: UniProtKB
Inflammatory response Source: UniProtKB
mRNA processing Source: ProtInc
Response to lipopolysaccharide Source: UniProtKB
Cellular Location
Nucleus. Component of ribonucleosomes.
PTM
Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA.
Arg-291 is dimethylated, probably to asymmetric dimethylarginine.
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Anti-HNRNPA0 antibodies

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Rabbit Anti-HNRNPA0 Recombinant Antibody (D26A2) (CBMAB-CP1054-LY)

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Target: HNRNPA0
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D26A2
Application*: WB, IP
Datasheet SDS

Mouse Anti-HNRNPA0 Recombinant Antibody (CBFYH-1620) (CBMAB-H2616-FY)

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Target: HNRNPA0
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBFYH-1620
Application*: WB
Datasheet SDS

Mouse Anti-HNRNPA0 (AA 139-183) Recombinant Antibody (CBFYH-1618) (CBMAB-H2614-FY)

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Target: HNRNPA0
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-1618
Application*: WB, IH
Datasheet SDS

Rabbit Anti-HNRNPA0 Recombinant Antibody (D8A3) (CBMAB-H2613-FY)

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Target: HNRNPA0
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D8A3
Application*: WB, IP, IF, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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