HOXA3

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene.

Full Name

HOMEOBOX A3

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Biological Process

Angiogenesis Source: UniProtKB
Animal organ formation Source: Ensembl
Anterior/posterior pattern specification Source: GO_Central
Blood vessel remodeling Source: Ensembl
Cartilage development Source: Ensembl
Embryonic skeletal system morphogenesis Source: GO_Central
Gene expression Source: Ensembl
Glossopharyngeal nerve morphogenesis Source: Ensembl
Parathyroid gland development Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Specification of animal organ position Source: Ensembl
Thymus development Source: Ensembl
Thyroid gland development Source: Ensembl

Cellular Location

Nucleus