HOXC8
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008]
Full Name
Homeobox C8
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Biological Process
Anterior/posterior pattern specification Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Neuron differentiation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Skeletal system morphogenesis Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Neuron differentiation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Skeletal system morphogenesis Source: Ensembl
Cellular Location
Nucleus
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Anti-HOXC8 antibodies
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Target: HOXC8
Specificity: Human
Target: HOXC8
Specificity: Human
Target: HOXC8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-614372
Application*: WB, E
Target: HOXC8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1825
Application*: E, EC, WB
Target: HOXC8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1823
Application*: SE, E, WB
Target: HOXC8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1D3
Application*: IP, M
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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