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HOXC8 Matched Antibody Pair (571) (APMAB-571LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-HOXC8 polyclonal antibody, 100 ug
Detection Antibody
Anti-HOXC8 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008]
Alternative Names
Homeobox C8; Homeobox Protein Hox-3A; Homeo Box C8; HOX3A; Hox-3.1, Mouse, Homolog Of; Homeobox Protein Hox-C8; Homeo Box 3A; HOX3;
Entrez Gene ID
3224
UniProt ID
P31273
More Infomation

Cui, W., Zhang, Q., Wang, H., Zhang, X., Tian, M., Liu, D., & Yang, X. (2023). Effects of HOXC8 on the Proliferation and Differentiation of Porcine Preadipocytes. Animals, 13(16), 2615.

Xu, D., Gao, C., Cao, Y., & Xiao, B. (2023). HOXC8 alleviates high glucose-triggered damage of trophoblast cells during gestational diabetes mellitus via activating TGFβ1-mediated Notch1 pathway. Human Cell, 36(1), 195-208.

Catela, C., Chen, Y., Weng, Y., Wen, K., & Kratsios, P. (2022). Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife, 11, e70766.

Li, M., Cai, J., Han, X., & Ren, Y. (2020). Downregulation of circNRIP1 suppresses the paclitaxel resistance of ovarian cancer via regulating the miR-211-5p/HOXC8 axis. Cancer management and research, 9159-9171.

Mihara, Y., Maekawa, R., Sato, S., Shimizu, N., Doi-Tanaka, Y., Takagi, H., ... & Sugino, N. (2020). An integrated genomic approach identifies HOXC8 as an upstream regulator in ovarian endometrioma. The Journal of Clinical Endocrinology & Metabolism, 105(12), e4474-e4489.

Yang, H., Cao, Y., Zhang, J., Liang, Y., Su, X., Zhang, C., ... & Fan, Z. (2020). DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013. Stem cell research & therapy, 11, 1-16.

Zhang, Q., Ni, T., Dang, Y., Ding, L., Jiang, J., Li, J., ... & Chen, Z. J. (2020). MiR-148a-3p may contribute to flawed decidualization in recurrent implantation failure by modulating HOXC8. Journal of Assisted Reproduction and Genetics, 37, 2535-2544.

Gong, C., Zou, J., Zhang, M., Zhang, J., Xu, S., Zhu, S., ... & Li, Y. (2019). Upregulation of MGP by HOXC8 promotes the proliferation, migration, and EMT processes of triple‐negative breast cancer. Molecular carcinogenesis, 58(10), 1863-1875.

Huang, Y., Chen, L., & Guo, A. (2018). Upregulated expression of HOXC8 is associated with poor prognosis of cervical cancer. Oncology letters, 15(5), 7291-7296.

Liu, H., Zhang, M., Xu, S., Zhang, J., Zou, J., Yang, C., ... & Li, Y. (2018). HOXC8 promotes proliferation and migration through transcriptional up-regulation of TGFβ1 in non-small cell lung cancer. Oncogenesis, 7(2), 1.

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For research use only. Not intended for any clinical use.

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