HSD17B2

HSD17B2 (Hydroxysteroid 17-Beta Dehydrogenase 2) is a Protein Coding gene. Diseases associated with HSD17B2 include Progesterone Resistance and Endometriosis Of Ovary. Among its related pathways are Androstenedione and testosterone biosynthesis and metabolism p.1 and Metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and testosterone dehydrogenase (NAD+) activity. An important paralog of this gene is HSD11B2.

hydroxysteroid (17-beta) dehydrogenase 2

Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.

Estrogen biosynthetic process Source: Reactome
In utero embryonic development Source: Ensembl
Placenta development Source: Ensembl
Response to retinoic acid Source: BHF-UCL

Membrane

Helical: 4-24