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HSD17B2

HSD17B2 (Hydroxysteroid 17-Beta Dehydrogenase 2) is a Protein Coding gene. Diseases associated with HSD17B2 include Progesterone Resistance and Endometriosis Of Ovary. Among its related pathways are Androstenedione and testosterone biosynthesis and metabolism p.1 and Metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and testosterone dehydrogenase (NAD+) activity. An important paralog of this gene is HSD11B2.

Full Name

hydroxysteroid (17-beta) dehydrogenase 2

Function

Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.

Biological Process

Estrogen biosynthetic process Source: Reactome
In utero embryonic development Source: Ensembl
Placenta development Source: Ensembl
Response to retinoic acid Source: BHF-UCL

Cellular Location

Membrane

Topology

Helical: 4-24

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Anti-HSD17B2 antibodies

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Mouse Anti-HSD17B2 Recombinant Antibody (CBFYH-2007) (CBMAB-H3018-FY)

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Target: HSD17B2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2007

Application*: WB, F

Mouse Hsd17b2 ELISA Kit (V2LY-0626-LY1868)

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Target: Hsd17b2

Sensitivity: 0.043 ng/mL

Detection Range: 0.1-35 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Mouse

Assay Type: Sandwich

Reactivity: Mouse

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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