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Mouse Anti-HSD17B2 Recombinant Antibody (CBFYH-2007) (CBMAB-H3018-FY)

This product is mouse antibody that recognizes HSD17B2. The antibody CBFYH-2007 can be used for immunoassay techniques such as: WB, FC.
See all HSD17B2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-2007
Antibody Isotype
IgG1
Application
WB, FC

Basic Information

Immunogen
Full length human recombinant protein of human HSD17B2 produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
hydroxysteroid (17-beta) dehydrogenase 2
Introduction
HSD17B2 (Hydroxysteroid 17-Beta Dehydrogenase 2) is a Protein Coding gene. Diseases associated with HSD17B2 include Progesterone Resistance and Endometriosis Of Ovary. Among its related pathways are Androstenedione and testosterone biosynthesis and metabolism p.1 and Metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and testosterone dehydrogenase (NAD+) activity. An important paralog of this gene is HSD11B2.
Entrez Gene ID
UniProt ID
Alternative Names
Hydroxysteroid 17-Beta Dehydrogenase 2; Short Chain Dehydrogenase/Reductase Family 9C Member 2; Microsomal 17-Beta-Hydroxysteroid Dehydrogenase; 17-Beta-Hydroxysteroid Dehydrogenase Type 2; 20 Alpha-Hydroxysteroid Dehydrogenase; Testosterone 17-Beta-Dehydrogenase; 17-Beta-HSD 2; 20-ALPHA-HSD; EDH17B2
Function
Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.
Biological Process
Estrogen biosynthetic process Source: Reactome
In utero embryonic development Source: Ensembl
Placenta development Source: Ensembl
Response to retinoic acid Source: BHF-UCL
Cellular Location
Membrane
Topology
Helical: 4-24
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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