KATNAL1

Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro (PubMed:26929214).

Full Name

Katanin Catalytic Subunit A1 Like 1

Function

Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity).
Has microtubule-severing activity in vitro (PubMed:26929214).

Biological Process

Microtubule severingManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:UniProtKB-UniRule

Cellular Location

Cytoplasm, cytoskeleton; Cytoplasm; Cytoplasm, cytoskeleton, spindle pole; Cytoplasm, cytoskeleton, spindle. Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity).
Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (PubMed:26929214).

Anti-KATNAL1 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-KATNAL1 Recombinant Antibody (6A4) (CBMAB-K0446-LY)

Datasheet

SDS

Target: KATNAL1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6A4

Application*: F, P, WB

Mouse Anti-KATNAL1 Recombinant Antibody (1A7) (CBMAB-K0443-LY)

Datasheet

SDS

Target: KATNAL1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat, Monkey

Clone: 1A7

Application*: WB, IH, F

Mouse Anti-KATNAL1 Recombinant Antibody (CBLY1-041) (CBMAB-K0442-LY)

Datasheet

SDS

Target: KATNAL1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBLY1-041

Application*: WB, IP, IF, E

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)