KATNAL1

Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro (PubMed:26929214).
Full Name
Katanin Catalytic Subunit A1 Like 1
Function
Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity).
Has microtubule-severing activity in vitro (PubMed:26929214).
Biological Process
Microtubule severingManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:UniProtKB-UniRule
Cellular Location
Cytoplasm, cytoskeleton; Cytoplasm; Cytoplasm, cytoskeleton, spindle pole; Cytoplasm, cytoskeleton, spindle. Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity).
Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (PubMed:26929214).
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Anti-KATNAL1 antibodies

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Mouse Anti-KATNAL1 Recombinant Antibody (6A4) (CBMAB-K0446-LY)

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Target: KATNAL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A4
Application*: F, P, WB
Datasheet SDS

Mouse Anti-KATNAL1 Recombinant Antibody (1A7) (CBMAB-K0443-LY)

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Target: KATNAL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Monkey
Clone: 1A7
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-KATNAL1 Recombinant Antibody (CBLY1-041) (CBMAB-K0442-LY)

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Target: KATNAL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLY1-041
Application*: WB, IP, IF, E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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