KLK3
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Full Name
Kallikrein Related Peptidase 3
Function
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Biological Process
Cellular protein metabolic processTAS:Reactome
Negative regulation of angiogenesis1 PublicationNAS:UniProtKB
Positive regulation of antibacterial peptide productionManual Assertion Based On ExperimentIDA:UniProtKB
ProteolysisManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of systemic arterial blood pressureManual Assertion Based On ExperimentIBA:GO_Central
Zymogen activationManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of angiogenesis1 PublicationNAS:UniProtKB
Positive regulation of antibacterial peptide productionManual Assertion Based On ExperimentIDA:UniProtKB
ProteolysisManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of systemic arterial blood pressureManual Assertion Based On ExperimentIBA:GO_Central
Zymogen activationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
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Anti-KLK3 antibodies
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CompareTarget: KLK3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: B732M
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF351
Application*: ELISA, IHC, WB
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 7D4
Application*: E, IH
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT1070
Application*: WB, P, IF, F, E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3017
Application*: F
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2721
Application*: IH, F
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A776
Application*: FC, IHC, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A775
Application*: Dot blot, ELISA, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A774
Application*: ELISA, IF, IHC
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0543
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYR0538
Application*: SE
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0537
Application*: SE
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYR0536
Application*: SE
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0535
Application*: SE
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0534
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0533
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0532
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0531
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0530
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0529
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0528
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0527
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYR0526
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0525
Application*: SE
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0454
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0453
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0452
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYR0451
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYR0450
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYR0449
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Application*: ELISA, WB, IHC
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A11E9, 5A11E2
Application*: ELISA, WB, IHC, FC
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RM323
Application*: ELISA, IHC, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: IHC654
Application*: P, E, IH
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D2A8
Application*: WB, IP, IF (IC)
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-2264
Application*: WB, P, IF
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: Pa3
Application*: WB, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cat
Clone: 1A7
Application*: E, WB, P, C
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.B.907
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.B.904
Application*: E, LF
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 7
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3
Application*: P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-1401
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 551CT16.3.5
Application*: WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TD11B3-4
Application*: C, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: PSAK3-1
Application*: IF, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: M701041
Application*: E, IH
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LT-3D2
Application*: E, F
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: KLK3/801+KLK3/1248
Application*: P, IF/IC, F
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: ER-PR8
Application*: IH
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EP1588Y
Application*: WB, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C3F12
Application*: P, C, IC, WB, F, ES
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: BSB-7
Application*: C, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BGN/PSA4
Application*: E, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT1D10
Application*: P, E, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A5D5
Application*: IH, P, C, IC, WB, F, ES
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 981
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 8A12
Application*: WB, F, E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 5F28
Application*: WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A11E9
Application*: WB, E, F, IH, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A11E2
Application*: E, WB, IH, F
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 58.10D6
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4A1E2
Application*: E, IH, IF
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 3C8
Application*: WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3A11
Application*: WB, IH
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B7
Application*: IH, P, IH, C, IC, WB, F, IA
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A2
Application*: WB, IH
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 251
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 214
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F7
Application*: P, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1B1
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A1
Application*: WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 181823
Application*: WB, IH, IP
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 181811
Application*: WB, E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L661
Application*: N, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 14i41
Application*: F, WB
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 113
Application*: E
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 103
Application*: P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 906
Application*: E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CHYH2
Application*: C, E, WB, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM352
Application*: WB, F, IC/IF, P, C
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Cat
Clone: 1A7/1A7G6B6
Application*: F, P
Target: KLK3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: BA0028
Application*: P, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: PSA 28/A4
Application*: C, P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: KLK3/801
Application*: P
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: PS2
Application*: E, E
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3E6
Application*: E, F, IF, C, P, WB
Target: KLK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A67-B/E3
Application*: F, IF, P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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