Human Recombinant KLK3 protein, His Tag-1 (V2LY-0526-LY5189)

Name: Human Recombinant KLK3 protein, His Tag-1
SKU: V2LY-0526-LY5189
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant KLK3 protein, His Tag consist of Amino Acid: 1-261 and predicts a molecular mass of 28.3 kDa.

Molecule Mass

28.3 kDa

Verified

HPLC

Sequence

Amino Acid: 1-261

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥90% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC. ≥90% as determined by SEC-MALS(Routinely tested).

Endotoxin

<0.05 EU/mg protein.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Kallikrein Related Peptidase 3

Function

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Biological Process

Cellular protein metabolic processTAS:Reactome
Negative regulation of angiogenesis1 PublicationNAS:UniProtKB
Positive regulation of antibacterial peptide productionManual Assertion Based On ExperimentIDA:UniProtKB
ProteolysisManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of systemic arterial blood pressureManual Assertion Based On ExperimentIBA:GO_Central
Zymogen activationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Secreted

Raimondo, S., Gentile, M., Esposito, G., Gentile, T., Ferrara, I., Crescenzo, C., ... & Montano, L. (2021). Could kallikrein-related serine peptidase 3 be an early biomarker of environmental exposure in young women?. International Journal of Environmental Research and Public Health, 18(16), 8833.

Koistinen, H., Künnapuu, J., & Jeltsch, M. (2021). KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not?. International Journal of Molecular Sciences, 22(24), 13545.

Motamedi, R. K., Sarhangi, N., Afshari, M., Sattari, M., Jamaldini, S. H., Samzadeh, M., ... & Hasanzad, M. (2019). Kallikarein‐related peptidase 3 common genetic variant and the risk of prostate cancer. Journal of Cellular Biochemistry, 120(9), 14822-14830.

Ding, W. H., Ren, K. W., Yue, C., Zou, J. G., Zuo, L., Zhang, L. F., ... & Mi, Y. Y. (2018). Association between three genetic variants in kallikrein 3 and prostate cancer risk. Bioscience reports, 38(6), BSR20181151.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-KLK3 Recombinant Antibody (CAT#: CBMAB-AO891LY)

Human Recombinant KLK3 protein, His Tag (CAT#: V2LY-0526-LY5188)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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