Klrb1c
KLRB1C (killer cell lectin-like receptor subfamily B member 1C) is a protein coding gene.
Full Name
killer cell lectin-like receptor subfamily B member 1C
Alternative Names
Nk1; Ly59; Nk-1; CD161; Ly-59; Ly55c; NK1.1; NKRP1; Nk1.2; Klrb1b; NK-RP1; Nk-1.2; Nkrp1b; Nkrp1c; ly-55c; NKRP140; AI462337; NKR-P1.9
Function
Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production.
Biological Process
Natural killer cell activationManual Assertion Based On ExperimentIDA:MGI
Positive regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIDA:MGI
Positive regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Membrane
Topology
Cytoplasmic: 1-45
Helical: 46-66
Extracellular: 67-223
Helical: 46-66
Extracellular: 67-223
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Anti-Klrb1c antibodies
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Target: Klrb1c
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: AG129
Application*: B, MC, F, IP, WB
Target: KLRB1C
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJN-1117
Application*: F
Target: Klrb1c
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: PK136
Application*: F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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