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Mouse Anti-Klrb1c Recombinant Antibody (PK136) (CBMAB-K0168-LY)

This product is antibody recognizes Klrb1c. The antibody PK136 immunoassay techniques such as: FC.
See all Klrb1c antibodies
Published Data
Fig.1 Immunophenotyping of splenic CD3+NK1.1+ population by flow cytometer.
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Fig.2 Cleaved caspase 3 stained proximal small intestine sections for WT mice treated with NK1.1 antibody for 24 h prior to 3 h 30 µg/g i.p.
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Fig.1 Choroids were explanted and immunohistochemically stained for isolectin B4 at day 10.
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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
PK136
Antibody Isotype
IgG2a, κ
Application
FC

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
killer cell lectin-like receptor subfamily B member 1C
Entrez Gene ID
17059
UniProt ID
P27814
Alternative Names
AI462337; CD161; Klrb1b; Ly-59; Ly55c; Ly59; NK-RP1; NK1.1; NKR-P1.9; NKRP1; NKRP140; Nk-1; Nk-1.2; Nk1; Nk1.2; Nkrp1b; Nkrp1c; ly-55c
Function
Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production.
Biological Process
Natural killer cell activationManual Assertion Based On ExperimentIDA:MGI
Positive regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Membrane
Topology
Cytoplasmic: 1-45
Helical: 46-66
Extracellular: 67-223
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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