loading...

LAMTOR3

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase cascade.

Full Name

LATE ENDOSOMAL/LYSOSOMAL ADAPTOR, MAPK AND MTOR ACTIVATOR 3

Function

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Biological Process

Cellular protein localizationManual Assertion Based On ExperimentIMP:UniProtKB
Cellular response to amino acid stimulusManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of MAPK cascadeIEA:Ensembl
Positive regulation of TOR signalingManual Assertion Based On ExperimentIMP:UniProtKB
Protein localization to cell junctionIEA:Ensembl

Cellular Location

Late endosome membrane

View more

Anti-LAMTOR3 antibodies

+ Filters

Loading...

Rabbit Anti-LAMTOR3 Recombinant Antibody (D38G5) (CBMAB-CP1347-LY)

Compare

Target: LAMTOR3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat, Monkey

Clone: D38G5

Application*: WB

Mouse Anti-LAMTOR3 Recombinant Antibody (2A4) (CBMAB-A5289-LY)

Compare

Target: LAMTOR3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2A4

Application*: WB, E

Mouse Anti-LAMTOR3 (AA 1-124) Recombinant Antibody (CBFYM-1207) (CBMAB-M1364-FY)

Compare

Target: LAMTOR3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse, Rat

Clone: CBFYM-1207

Application*: E, WB

Mouse Anti-LAMTOR3 Recombinant Antibody (CBYJL-1181) (CBMAB-L0680-YJ)

Compare

Target: LAMTOR3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJL-1181

Application*: E, WB

Mouse Anti-LAMTOR3 Recombinant Antibody (CBYJL-1180) (CBMAB-L0679-YJ)

Compare

Target: LAMTOR3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJL-1180

Application*: E, WB

Rabbit Anti-LAMTOR3 Recombinant Antibody (CBYJL-1179) (CBMAB-L0678-YJ)

Compare

Target: LAMTOR3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat, Monkey

Clone: CBYJL-1179

Application*: WB

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry