LANCL2

LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.
Full Name
LanC Like 2
Function
Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.
Biological Process
Carbohydrate metabolic processIEA:InterPro
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of abscisic acid-activated signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Cytoplasm
Cell membrane
Localizes to the juxta-nuclear vesicles (PubMed:16979580).
Associates with the cortical actin cytoskeleton (PubMed:16979580).
Cholesterol depletion by methyl-beta-cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo (PubMed:16979580).
Membrane-association is important for the increased cellular sensitivity to an anticancer drug (adriamycin) (PubMed:16979580).
PTM
Myristoylated. Essential for membrane association.
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Anti-LANCL2 antibodies

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Mouse Anti-LANCL2 Recombinant Antibody (CBYJT-1414) (CBMAB-T0437-YJ)

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Target: LANCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1414
Application*: F, P, WB
Datasheet SDS

Mouse Anti-LANCL2 Recombinant Antibody (CBYJT-1413) (CBMAB-T0436-YJ)

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Target: LANCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1413
Application*: P, WB
Datasheet SDS

Mouse Anti-LANCL2 Recombinant Antibody (CBYJL-1184) (CBMAB-L0685-YJ)

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Target: LANCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1184
Application*: WB, P, F
Datasheet SDS

Mouse Anti-LANCL2 Recombinant Antibody (1C5) (CBMAB-L0684-YJ)

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Target: LANCL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C5
Application*: WB, IH
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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