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LANCL2

LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.

Full Name

LanC Like 2

Function

Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.

Biological Process

Carbohydrate metabolic processIEA:InterPro
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of abscisic acid-activated signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Nucleus
Cytoplasm
Cell membrane
Localizes to the juxta-nuclear vesicles (PubMed:16979580).
Associates with the cortical actin cytoskeleton (PubMed:16979580).
Cholesterol depletion by methyl-beta-cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo (PubMed:16979580).
Membrane-association is important for the increased cellular sensitivity to an anticancer drug (adriamycin) (PubMed:16979580).

PTM

Myristoylated. Essential for membrane association.

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Anti-LANCL2 antibodies

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Mouse Anti-LANCL2 Recombinant Antibody (CBYJT-1414) (CBMAB-T0437-YJ)

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Target: LANCL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1414

Application*: F, P, WB

Mouse Anti-LANCL2 Recombinant Antibody (CBYJT-1413) (CBMAB-T0436-YJ)

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Target: LANCL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1413

Application*: P, WB

Mouse Anti-LANCL2 Recombinant Antibody (CBYJL-1184) (CBMAB-L0685-YJ)

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Target: LANCL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1184

Application*: WB, P, F

Mouse Anti-LANCL2 Recombinant Antibody (1C5) (CBMAB-L0684-YJ)

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Target: LANCL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1C5

Application*: WB, IH

More Infomation

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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