LHX6

This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. [provided by RefSeq]

LIM homeobox 6

Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity).

Cell maturationISS:UniProtKB
Cerebral cortex GABAergic interneuron migrationISS:UniProtKB
Cerebral cortex radially oriented cell migrationISS:UniProtKB
Cerebral cortex tangential migrationISS:UniProtKB
Forebrain neuron developmentManual Assertion Based On ExperimentIBA:GO_Central
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Nucleus