LRRFIP1
LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. It may control smooth muscle cells proliferation following artery injury through PDGFA repression. It may also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Full Name
LRRFIP1
Function
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Biological Process
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Cytoplasm
Cytoplasm
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Anti-LRRFIP1 antibodies
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CompareTarget: Lrrfip1
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYJL-2590
Application*: WB, IP, IF, E
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT849
Application*: WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: A940
Application*: WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A939
Application*: ELISA, WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D3
Application*: WB, E
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-1421
Application*: E, IF, WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBYCL-486
Application*: E, WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYCL-485
Application*: WB, E, P, F, IC, IF
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBYCL-484
Application*: WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2032
Application*: WB, IP, IF, E
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 4F3-D8-C9
Application*: WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-2031
Application*: E, WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3E1
Application*: IF, WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2029
Application*: E, IF, WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-2028
Application*: E, IF, IH, WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBYJL-2027
Application*: WB
Target: LRRFIP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3A8
Application*: IP, M
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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