LSM14A

LSM14A is essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs.

LSM14A, mRNA processing body assembly factor

Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation (PubMed:16484376, PubMed:17074753, PubMed:29510985).
Acts as a repressor of mRNA translation (PubMed:29510985).
May play a role in mitotic spindle assembly (PubMed:26339800).

Mitotic spindle assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of translationManual Assertion Based On ExperimentIMP:UniProtKB
P-body assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of type I interferon-mediated signaling pathwayIEA:Ensembl
RIG-I signaling pathwayIEA:Ensembl
Stress granule assemblyManual Assertion Based On ExperimentIBA:GO_Central

Cytoplasm, P-body
Cytoplasm, cytoskeleton, spindle
Cytoplasm, Stress granule