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LSM14A

LSM14A is essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs.
Full Name
LSM14A, mRNA processing body assembly factor
Function
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation (PubMed:16484376, PubMed:17074753, PubMed:29510985).
Acts as a repressor of mRNA translation (PubMed:29510985).
May play a role in mitotic spindle assembly (PubMed:26339800).
Biological Process
Mitotic spindle assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of translationManual Assertion Based On ExperimentIMP:UniProtKB
P-body assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of type I interferon-mediated signaling pathwayIEA:Ensembl
RIG-I signaling pathwayIEA:Ensembl
Stress granule assemblyManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, P-body
Cytoplasm, cytoskeleton, spindle
Cytoplasm, Stress granule
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Anti-LSM14A antibodies

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Mouse Anti-LSM14A Recombinant Antibody (G-5) (CBMAB-R0581-CN)

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Target: LSM14A
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: G-5
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-LSM14A Recombinant Antibody (C-5) (CBMAB-R0580-CN)

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Target: LSM14A
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: C-5
Application*: WB, IP, IF, E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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