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LSM14A

LSM14A is essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs.

Full Name

LSM14A, mRNA processing body assembly factor

Function

Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation (PubMed:16484376, PubMed:17074753, PubMed:29510985).
Acts as a repressor of mRNA translation (PubMed:29510985).
May play a role in mitotic spindle assembly (PubMed:26339800).

Biological Process

Mitotic spindle assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of translationManual Assertion Based On ExperimentIMP:UniProtKB
P-body assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of type I interferon-mediated signaling pathwayIEA:Ensembl
RIG-I signaling pathwayIEA:Ensembl
Stress granule assemblyManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm, P-body
Cytoplasm, cytoskeleton, spindle
Cytoplasm, Stress granule

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Anti-LSM14A antibodies

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Mouse Anti-LSM14A Recombinant Antibody (G-5) (CBMAB-R0581-CN)

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Target: LSM14A

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: G-5

Application*: WB, IP, IF, E

Mouse Anti-LSM14A Recombinant Antibody (C-5) (CBMAB-R0580-CN)

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Target: LSM14A

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: C-5

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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