LSM8

LSM8 is a member of the like-Sm family of proteins. LSM8 consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.
Full Name
LSM8 homolog, U6 small nuclear RNA associated
Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166).
The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).
Biological Process
mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
RNA metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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Anti-LSM8 antibodies

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Mouse Anti-LSM8 Recombinant Antibody (CBYJL-2089) (CBMAB-L2231-YJ)

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Target: LSM8
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYJL-2089
Application*: WB, IP, IF, P, E
Datasheet SDS

Mouse Anti-LSM8 Recombinant Antibody (CBYJL-2088) (CBMAB-L2230-YJ)

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Target: LSM8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2088
Application*: IC, WB
Datasheet SDS

Mouse Anti-LSM8 Recombinant Antibody (2527C6a) (CBMAB-L2229-YJ)

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Target: LSM8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2527C6a
Application*: DB, IC, IF, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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