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LYPD6B

LYPD6B is believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-33:beta-42 nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-32:alpha-5:beta-42 nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.

Full Name

LY6/PLAUR domain containing 6B

Function

Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.

Cellular Location

Cell membrane

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Anti-LYPD6B antibodies

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Mouse Anti-LYPD6B Recombinant Antibody (CBYCL-595) (CBMAB-L0496-YC)

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Target: LYPD6B

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYCL-595

Application*: P, WB

Mouse Anti-LYPD6B Recombinant Antibody (CBYCL-594) (CBMAB-L0495-YC)

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Target: LYPD6B

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse

Clone: CBYCL-594

Application*: WB, P

Mouse Anti-LYPD6B Recombinant Antibody (634CT7.10.1) (CBMAB-L2504-YJ)

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Target: LYPD6B

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse

Clone: 634CT7.10.1

Application*: E, WB

Human Recombinant LYPD6B protein, Biotin Conjugated, His & AVI Tag (V2LY-0526-LY5409)

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Target: LYPD6B

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-164

Tag: His & AVI Tag

Cynomolgus Recombinant LYPD6B protein, Biotin Conjugated, His & AVI Tag (V2LY-0526-LY1602)

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Target: LYPD6B

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-150

Tag: His & AVI Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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