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Mouse Anti-LYPD6B Recombinant Antibody (634CT7.10.1) (CBMAB-L2504-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Ly6/Plaur Domain Containing 6B (LYPD6B). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all LYPD6B antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
634CT7.10.1
Antibody Isotype
IgG2b
Application
ELISA, WB

Basic Information

Immunogen
LYPD6B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the Central region of human LYPD6B.
Specificity
Human, Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 79-109

Target

Full Name
LY6/PLAUR domain containing 6B
Introduction
LYPD6B is believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-33:beta-42 nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-32:alpha-5:beta-42 nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
Entrez Gene ID
Human130576
Mouse71897
UniProt ID
HumanQ8NI32
MouseQ9D7F2
Alternative Names
CT116; LYPD7
Function
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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