MAGI1
The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Full Name
membrane associated guanylate kinase, WW and PDZ domain containing 1
Function
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
Biological Process
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of cell-cell adhesionManual Assertion Based On ExperimentIDA:ARUK-UCL
Protein-containing complex assembly1 PublicationNAS:ProtInc
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of cell-cell adhesionManual Assertion Based On ExperimentIDA:ARUK-UCL
Protein-containing complex assembly1 PublicationNAS:ProtInc
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell junction, tight junction
Cell membrane
Localizes to epithelial cells tight junctions.
Cell membrane
Localizes to epithelial cells tight junctions.
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Anti-MAGI1 antibodies
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Target: MAGI1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: 7B4
Application*: WB, E
Target: MAGI1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0539
Application*: E, WB
Target: MAGI1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0489
Application*: E, IC, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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