MAP6D1
This gene encodes a protein highly similar to the mouse MAP6 domain containing 1 protein, which is related to the STOP proteins. Based on the study of the mouse protein, the encoded protein may function as a calmodulin-regulated neuronal protein that binds and stabilizes microtubules but also associates with the Golgi membranes through N-terminal palmitoylation.
Full Name
MAP6 DOMAIN CONTAINING 1
Function
May have microtubule-stabilizing activity.
Biological Process
Cytoskeleton-dependent intracellular transportManual Assertion Based On ExperimentIBA:GO_Central
Microtubule cytoskeleton organizationIEA:InterPro
N-terminal peptidyl-L-cysteine N-palmitoylationIEA:Ensembl
Negative regulation of microtubule depolymerizationIEA:Ensembl
Regulation of microtubule cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Microtubule cytoskeleton organizationIEA:InterPro
N-terminal peptidyl-L-cysteine N-palmitoylationIEA:Ensembl
Negative regulation of microtubule depolymerizationIEA:Ensembl
Regulation of microtubule cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Golgi apparatus
Cytoplasm, cytoskeleton
Colocalizes with microtubules.
Cytoplasm, cytoskeleton
Colocalizes with microtubules.
PTM
Palmitoylated. Palmitoylation enhances association with microtubules.
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Anti-MAP6D1 antibodies
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Target: MAP6D1
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBFYM-1559
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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