METRN
Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis.
Full Name
METEORIN, GLIAL CELL DIFFERENTIATION REGULATOR
Function
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity).
Biological Process
Glial cell differentiation Source: GO_Central
Positive regulation of axonogenesis Source: GO_Central
Positive regulation of axonogenesis Source: GO_Central
Cellular Location
Secreted
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Anti-METRN antibodies
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Target: METRN
Sensitivity: 0.024 ng/mL
Detection Range: 0.05-30 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Metrn
Sensitivity: 0.015 ng/mL
Detection Range: 0.03-9 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
Target: METRN
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 22-291
Tag: hFc Tag
Target: METRN
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYM-2119
Application*: E, WB
Target: METRN
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYM-2118
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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