Rat Anti-METRN Recombinant Antibody (CBFYM-2119) (CBMAB-M2301-FY)

Name: Rat Anti-METRN Recombinant Antibody (CBFYM-2119)
SKU: CBMAB-M2301-FY
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Rat

Specificity

Mouse

Clone

CBFYM-2119

Antibody Isotype

IgG2b

Application

ELISA, WB

Basic Information

Immunogen

Recombinant mouse Meteorin

Specificity

Mouse

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

METEORIN, GLIAL CELL DIFFERENTIATION REGULATOR

Introduction

Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis.

Entrez Gene ID

79006

UniProt ID

Q9UJH8

Alternative Names

Meteorin, Glial Cell Differentiation Regulator; C16orf23; Chromosome 16 Open Reading Frame 23; C380A1.2; Meteorin

Function

Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity).

Biological Process

Glial cell differentiation Source: GO_Central
Positive regulation of axonogenesis Source: GO_Central

Cellular Location

Secreted

More Infomation

References

Wang, X., Cao, Q., Shi, Y., Wu, X., Mi, Y., Liu, K., ... & Zhang, M. (2021). Identification of low-dose radiation-induced exosomal circ-METRN and miR-4709-3p/GRB14/PDGFRα pathway as a key regulatory mechanism in Glioblastoma progression and radioresistance: Functional validation and clinical theranostic significance. International Journal of Biological Sciences, 17(4), 1061.

Xu, X., Zhang, C., Xia, Y., & Yu, J. (2020). Over expression of METRN predicts poor clinical prognosis in colorectal cancer. Molecular Genetics & Genomic Medicine, 8(3), e1102.

Cao, Q., Shi, Y., Wang, X., Yang, J., Mi, Y., Zhai, G., & Zhang, M. (2019). Circular METRN RNA hsa_circ_0037251 promotes glioma progression by sponging miR-1229-3p and regulating mTOR expression. Scientific Reports, 9(1), 19791.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Rat Anti-METRN (AA 22-291) Recombinant Antibody (CBFYM-2118)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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