MNX1

This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Full Name
MOTOR NEURON AND PANCREAS HOMEOBOX 1
Function
Putative transcription factor involved in pancreas development and function.
Biological Process
Central nervous system development Source: GO_Central
Endocrine pancreas development Source: GO_Central
Neuron projection morphogenesis Source: GO_Central
Spinal cord motor neuron cell fate specification Source: GO_Central
Cellular Location
Nucleus
Involvement in disease
Currarino syndrome (CURRAS):
The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.
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Anti-MNX1 antibodies

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Mouse Anti-MNX1 Recombinant Antibody (CBFYH-2654) (CBMAB-H3698-FY)

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Target: MNX1
Host: Mouse
Specificity: Human
Clone: CBFYH-2654
Application*: WB, IP, IF, E
Datasheet SDS

Rabbit Anti-MNX1 (C-terminus) Recombinant Antibody (CBFYM-2444) (CBMAB-M2631-FY)

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Target: MNX1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Human
Clone: CBFYM-2444
Application*: WB, IP, P
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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