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MS4A12

The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene.

Full Name

MEMBRANE SPANNING 4-DOMAINS A12

Function

May be involved in signal transduction as a component of a multimeric receptor complex.

Biological Process

Cell surface receptor signaling pathway Source: GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-91
Helical: 92-112
Extracellular: 113-120
Helical: 121-141
Cytoplasmic: 142-160
Helical: 161-181
Extracellular: 182-200
Helical: 201-221
Cytoplasmic: 222-267

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Anti-MS4A12 antibodies

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Mouse Anti-MS4A12 Recombinant Antibody (CBFYM-2604) (CBMAB-M2792-FY)

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Target: MS4A12

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-2604

Application*: WB, IH

Mouse Anti-MS4A12 Recombinant Antibody (CBFYM-0729) (CBMAB-M0871-FY)

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Target: MS4A12

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-0729

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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