Mouse Anti-MS4A12 Recombinant Antibody (CBFYM-0729) (CBMAB-M0871-FY)

This product is mouse antibody that recognizes MS4A12. The antibody CBFYM-0729 can be used for immunoassay techniques such as: ELISA, WB.
See all MS4A12 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-0729

Antibody Isotype

IgG1, k

Application

ELISA, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG1, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MEMBRANE SPANNING 4-DOMAINS A12

Introduction

The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

54860

UniProt ID

Q9NXJ0

Alternative Names

Membrane Spanning 4-Domains A12; Membrane-Spanning 4-Domains, Subfamily A, Member 12; Membrane-Spanning 4-Domains Subfamily A Member 12; Ms4a10

Function

May be involved in signal transduction as a component of a multimeric receptor complex.

Biological Process

Cell surface receptor signaling pathway Source: GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-91
Helical: 92-112
Extracellular: 113-120
Helical: 121-141
Cytoplasmic: 142-160
Helical: 161-181
Extracellular: 182-200
Helical: 201-221
Cytoplasmic: 222-267

References

Liu, S., Jiang, T., Yuan, Y., Yu, H., Guo, Z., Gao, Y., ... & Xiao, W. (2022). Membrane spanning 4 domains A12 (MS4A12) c. C211T stop-gain single-nucleotide polymorphism (rs2298553) promotes metastasis in colorectal cancer via the Hippo pathway. Cancer Research, 82(12_Supplement), 5987-5987.

Han, J. W., Heo, W., Lee, D., Kang, C., Kim, H. Y., Jun, I., ... & Kim, J. Y. (2021). Plasma Membrane Localized GCaMP-MS4A12 by Orai1 Co-Expression Shows Thapsigargin-and Ca2+-Dependent Fluorescence Increases. Molecules and Cells, 44(4), 223.

Han, J., Zhang, X., Liu, Y., Jing, L., Liu, Y. B., & Feng, L. (2020). CLCA4 and MS4A12 as the significant gene biomarkers of primary colorectal cancer. Bioscience reports, 40(8), BSR20200963.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-MS4A12 Recombinant Antibody (CBFYM-0729)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-MS4A12 Recombinant Antibody (CBFYM-2604)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: