MYO1D

MYO1D (Myosin ID) is a Protein Coding gene. Diseases associated with MYO1D include Visceral Heterotaxy. Among its related pathways are PAK Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is MYO1G.

Full Name

MYOSIN ID

Function

Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity).

Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity).

Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity).

Biological Process

Actin filament organization Source: GO_Central
Cellular localization Source: UniProtKB
Early endosome to recycling endosome transport Source: UniProtKB
Protein transport Source: UniProtKB-KW
Vesicle transport along actin filament Source: GO_Central

Cellular Location

Cytoplasm
Endosome
Early endosome
Other locations
Perikaryon
dendrite
cell cortex
Note: Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane. Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles.