Mouse Anti-MYO1D Recombinant Antibody (CBFYM-2985) (CBMAB-M3180-FY)

This product is mouse antibody that recognizes MYO1D. The antibody CBFYM-2985 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all MYO1D antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2985

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MYOSIN ID

Introduction

MYO1D is a Protein Coding gene. Diseases associated with MYO1D include Visceral Heterotaxy. Among its related pathways are PAK Pathway and ERK Signaling. Gene Ontology annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is MYO1G.

Entrez Gene ID

4642

UniProt ID

O94832

Alternative Names

Myosin ID; Protein Phosphatase 1, Regulatory Subunit 108; Unconventional Myosin-Id; Myosin-I Gamma; PPP1R108; KIAA0727; Myr4

Function

Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity).

Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity).

Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity).

Biological Process

Actin filament organization Source: GO_Central
Cellular localization Source: UniProtKB
Early endosome to recycling endosome transport Source: UniProtKB
Protein transport Source: UniProtKB-KW
Vesicle transport along actin filament Source: GO_Central

Cellular Location

Cytoplasm
Endosome
Early endosome
Other locations
Perikaryon
dendrite
cell cortex
Note: Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane. Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles.

References

Feng, X., Du, W., Ding, M., Zhao, W., Xirefu, X., Ma, M., ... & Mi, N. (2022). Myosin 1D and the branched actin network control the condensation of p62 bodies. Cell Research, 32(7), 659-669.

Ko, Y. S., Bae, J. A., Kim, K. Y., Kim, S. J., Sun, E. G., Lee, K. H., ... & Kim, K. K. (2019). MYO1D binds with kinase domain of the EGFR family to anchor them to plasma membrane before their activation and contributes carcinogenesis. Oncogene, 38(49), 7416-7432.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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