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NIFK

This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.
Full Name
NUCLEOLAR PROTEIN INTERACTING WITH THE FHA DOMAIN OF MKI67
Biological Process
Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Protein-containing complex assembly1 PublicationNAS:UniProtKB
rRNA metabolic process1 PublicationNAS:UniProtKB
rRNA transcription1 PublicationNAS:UniProtKB
Cellular Location
Nucleus, nucleolus
Chromosome
Localizes to mitotic chromosomes in conjunction with MKI67.
PTM
Sequentially phosphorylated on Thr-238, Thr-234 and Ser-230. Thr-234 is phosphorylated only when Thr-238 is phosphorylated. Likewise, phosphorylation at Ser-230 requires that Thr-234 and Thr-238 are phosphorylated. Phosphorylation enhances MKI67 binding.
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Anti-NIFK antibodies

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Mouse Anti-NIFK Recombinant Antibody (CBWJN-0585) (CBMAB-N2465-WJ)

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Target: NIFK
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJN-0585
Application*: IH, IF
Datasheet SDS

Mouse Anti-NIFK Recombinant Antibody (CBWJN-0584) (CBMAB-N2464-WJ)

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Target: NIFK
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0584
Application*: WB, IH
Datasheet SDS

Mouse Anti-NIFK Recombinant Antibody (CBWJN-0551) (CBMAB-N2463-WJ)

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Target: NIFK
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0551
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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