Mouse Anti-NIFK Recombinant Antibody (CBWJN-0584) (CBMAB-N2464-WJ)

Name: Mouse Anti-NIFK Recombinant Antibody (CBWJN-0584)
SKU: CBMAB-N2464-WJ
Rating: 5 (1 reviews)

See all NIFK antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBWJN-0584

Application

WB, IHC

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

NUCLEOLAR PROTEIN INTERACTING WITH THE FHA DOMAIN OF MKI67

Introduction

This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.[provided by RefSeq, Jan 2009]

Entrez Gene ID

84365

UniProt ID

Q9BYG3

Alternative Names

Nucleolar Protein Interacting With The FHA Domain Of MKI67; Nucleolar Protein Interacting With The FHA Domain Of PKi-67; Nucleolar Phosphoprotein Nopp34; MKI67IP; Nopp34; HNIFK; MKI67 (FHA Domain) Interacting Nucleolar Phosphoprotein; MKI67 FHA Domain-Interacting Nucleolar Phosphoprotein;

Biological Process

Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Protein-containing complex assembly1 PublicationNAS:UniProtKB
rRNA metabolic process1 PublicationNAS:UniProtKB
rRNA transcription1 PublicationNAS:UniProtKB

Cellular Location

Nucleus, nucleolus
Chromosome
Localizes to mitotic chromosomes in conjunction with MKI67.

PTM

Sequentially phosphorylated on Thr-238, Thr-234 and Ser-230. Thr-234 is phosphorylated only when Thr-238 is phosphorylated. Likewise, phosphorylation at Ser-230 requires that Thr-234 and Thr-238 are phosphorylated. Phosphorylation enhances MKI67 binding.

Xia, T., Wang, B., & Sun, L. (2024). The nucleolar protein NIFK accelerates the progression of colorectal cancer via activating MYC pathway. Bioscience, Biotechnology, and Biochemistry, 88(1), 26-36.

Tan, L., He, Y., Wu, L., Liu, S., Peng, P., & Huang, J. (2023). NIFK as a potential prognostic biomarker in colorectal cancer correlating with immune infiltrates. Medicine, 102(40), e35452.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-NIFK Recombinant Antibody (CBWJN-0584)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-NIFK Recombinant Antibody (CBWJN-0551) (CAT#: CBMAB-N2463-WJ)

Mouse Anti-NIFK Recombinant Antibody (CBWJN-0585) (CAT#: CBMAB-N2465-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry