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Mouse Anti-NIFK Recombinant Antibody (CBWJN-0551) (CBMAB-N2463-WJ)

This product is a Mouse antibody that recognizes NIFK. The antibody CBWJN-0551 can be used for immunoassay techniques such as: WB.
See all NIFK antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJN-0551
Antibody Isotype
IgG1, κ
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.05% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NUCLEOLAR PROTEIN INTERACTING WITH THE FHA DOMAIN OF MKI67
Introduction
This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.[provided by RefSeq, Jan 2009]
Entrez Gene ID
84365
UniProt ID
Q9BYG3
Alternative Names
Nucleolar Protein Interacting With The FHA Domain Of MKI67; Nucleolar Protein Interacting With The FHA Domain Of PKi-67; Nucleolar Phosphoprotein Nopp34; MKI67IP; Nopp34; HNIFK; MKI67 (FHA Domain) Interacting Nucleolar Phosphoprotein; MKI67 FHA Domain-Interacting Nucleolar Phosphoprotein;
Biological Process
Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Protein-containing complex assembly1 PublicationNAS:UniProtKB
rRNA metabolic process1 PublicationNAS:UniProtKB
rRNA transcription1 PublicationNAS:UniProtKB
Cellular Location
Nucleus, nucleolus
Chromosome
Localizes to mitotic chromosomes in conjunction with MKI67.
PTM
Sequentially phosphorylated on Thr-238, Thr-234 and Ser-230. Thr-234 is phosphorylated only when Thr-238 is phosphorylated. Likewise, phosphorylation at Ser-230 requires that Thr-234 and Thr-238 are phosphorylated. Phosphorylation enhances MKI67 binding.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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