NINJ2
The protein encoded by this gene belongs to the ninjurin (for nerve injury induced) family. It is a cell surface adhesion protein that is upregulated in Schwann cells surrounding the distal segment of injured nerve, and promotes neurite outgrowth, thus may have a role in nerve regeneration after nerve injury. [provided by RefSeq, Oct 2011]
Full Name
Ninjurin 2
Function
Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Neuron cell-cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Tissue regenerationIEA:InterPro
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Neuron cell-cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Tissue regenerationIEA:InterPro
Cellular Location
Membrane
Topology
Extracellular: 1-65
Helical: 66-88
Cytoplasmic: 89-106
Helical: 107-127
Extracellular: 128-142
Helical: 66-88
Cytoplasmic: 89-106
Helical: 107-127
Extracellular: 128-142
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Anti-NINJ2 antibodies
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Target: NINJ2
Sensitivity: 0.0077 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: NINJ2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: A1364
Application*: ELISA, IHC, WB
Target: NINJ2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF310
Application*: ELISA, WB, IHC
Target: NINJ2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5C5B2
Application*: E, WB, IH
Target: NINJ2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-0057
Application*: IP, WB
Target: NINJ2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2B10
Application*: IP, WB, M
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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