NKX2-3

NKX2C is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions. See Harvey (1996) [PubMed 8812123] for a review of the structure, regulation, function, and evolution of NK2 homeobox genes with an emphasis on their roles in heart development.[supplied by OMIM

Full Name

NK2 transcription factor related, locus 3 (Drosophila)

Function

Transcription factor.

Biological Process

CD4-positive, alpha-beta T cell differentiationIEA:Ensembl
Cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Gland morphogenesisIEA:Ensembl
Leukocyte homeostasisIEA:Ensembl
Leukocyte migrationIEA:Ensembl
Lymph node developmentIEA:Ensembl
Macrophage differentiationIEA:Ensembl
Odontogenesis of dentin-containing toothIEA:Ensembl
Peyer's patch developmentIEA:Ensembl
Plasma cell differentiationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Post-embryonic digestive tract morphogenesisIEA:Ensembl
Regulation of cell population proliferationIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Spleen developmentIEA:Ensembl
Triglyceride metabolic processIEA:Ensembl

Cellular Location

Nucleus