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NME5

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).

Full Name

non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)

Function

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).

Biological Process

Cilium assemblyIEA:Ensembl
CTP biosynthetic processIEA:InterPro
Epithelial cilium movement involved in extracellular fluid movementIEA:Ensembl
GTP biosynthetic processIEA:InterPro
Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Nucleoside metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Spermatid developmentISS:UniProtKB
SpermatogenesisManual Assertion Based On ExperimentTAS:ProtInc
UTP biosynthetic processIEA:InterPro
Ventricular system developmentIEA:Ensembl

Cellular Location

Cell projection, cilium

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Anti-NME5 antibodies

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Mouse Anti-NME5 Recombinant Antibody (4F5) (CBMAB-N2795-WJ)

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Target: NME5

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4F5

Application*: E, IP, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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