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NME5

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
Full Name
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
Function
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
Biological Process
Cilium assemblyIEA:Ensembl
CTP biosynthetic processIEA:InterPro
Epithelial cilium movement involved in extracellular fluid movementIEA:Ensembl
GTP biosynthetic processIEA:InterPro
Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Nucleoside metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Spermatid developmentISS:UniProtKB
SpermatogenesisManual Assertion Based On ExperimentTAS:ProtInc
UTP biosynthetic processIEA:InterPro
Ventricular system developmentIEA:Ensembl
Cellular Location
Cell projection, cilium

Anti-NME5 antibodies

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Target: NME5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F5
Application*: E, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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