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Mouse Anti-NME5 Recombinant Antibody (4F5) (CBMAB-N2795-WJ)

This product is a Mouse antibody that recognizes NME5. The antibody 4F5 can be used for immunoassay techniques such as: ELISA, IP, WB.
See all NME5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4F5
Antibody Isotype
IgG2a, κ
Application
ELISA, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
Introduction
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
Entrez Gene ID
8382
UniProt ID
P56597
Alternative Names
NME/NM23 Family Member 5; Non-Metastatic Cells 5, Protein Expressed In (Nucleoside-Diphosphate Kinase); Inhibitor Of P53-Induced Apoptosis-Beta; Testis-Specific Nm23 Homolog; NDP Kinase Homolog 5; IPIA-Beta; NDK-H 5; NM23-H5;
Function
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
Biological Process
Cilium assemblyIEA:Ensembl
CTP biosynthetic processIEA:InterPro
Epithelial cilium movement involved in extracellular fluid movementIEA:Ensembl
GTP biosynthetic processIEA:InterPro
Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Nucleoside metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Spermatid developmentISS:UniProtKB
SpermatogenesisManual Assertion Based On ExperimentTAS:ProtInc
UTP biosynthetic processIEA:InterPro
Ventricular system developmentIEA:Ensembl
Cellular Location
Cell projection, cilium
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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