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NQO2

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Full Name
N-Ribosyldihydronicotinamide:Quinone Reductase 2
Function
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Biological Process
Quinone catabolic processManual Assertion Based On ExperimentIDA:CAFA
Cellular Location
Cytoplasm

Anti-NQO2 antibodies

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Mouse Anti-NQO2 Recombinant Antibody (1G2) (CBMAB-N3306-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: 1G2
Application*: IF, P, WB

Mouse Anti-NQO2 Recombinant Antibody (3E8-G2) (CBMAB-A6091-LY)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3E8-G2
Application*: WB, E

Mouse Anti-NQO2 Recombinant Antibody (1E3) (CBMAB-N0509-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 1E3
Application*: WB, E

Mouse Anti-NQO2 Recombinant Antibody (AT1E3) (CBMAB-N3314-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: AT1E3
Application*: E, WB

Mouse Anti-NQO2 Recombinant Antibody (11H4) (CBMAB-N3305-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 11H4
Application*: E, WB

Mouse Anti-NQO2 Recombinant Antibody (3A7) (CBMAB-N3307-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A7
Application*: WB

Mouse Anti-NQO2 Recombinant Antibody (3C11) (CBMAB-N3308-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: 3C11
Application*: WB

Mouse Anti-NQO2 Recombinant Antibody (CBWJN-0366) (CBMAB-N3309-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0366
Application*: E, WB

Mouse Anti-NQO2 Recombinant Antibody (3G4) (CBMAB-N3311-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Mouse
Clone: 3G4
Application*: WB, IH, P

Mouse Anti-NQO2 Recombinant Antibody (4B2) (CBMAB-N3312-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4B2
Application*: WB

Mouse Anti-NQO2 Recombinant Antibody (5F6) (CBMAB-N3313-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F6
Application*: IF, WB

Mouse Anti-NQO2 Recombinant Antibody (CBWJN-0766) (CBMAB-N3316-WJ)

Datasheet SDS
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0766
Application*: E, WB

NQO2 Matched Antibody Pair (815) (APMAB-815LY)

Datasheet SDS
Target: NQO2
Specificity: Human

NQO2 Matched Antibody Pair (816) (APMAB-816LY)

Datasheet SDS
Target: NQO2
Specificity: Human
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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