NQO2

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Full Name
N-Ribosyldihydronicotinamide:Quinone Reductase 2
Function
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Biological Process
Quinone catabolic processManual Assertion Based On ExperimentIDA:CAFA
Cellular Location
Cytoplasm
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Anti-NQO2 antibodies

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Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3E8-G2
Application*: WB, E
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0766
Application*: E, WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: AT1E3
Application*: E, WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F6
Application*: IF, WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4B2
Application*: WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Mouse
Clone: 3G4
Application*: WB, IH, P
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0366
Application*: E, WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: 3C11
Application*: WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A7
Application*: WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: 1G2
Application*: IF, P, WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 11H4
Application*: E, WB
Target: NQO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 1E3
Application*: WB, E
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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