Mouse Anti-NQO2 Recombinant Antibody (3E8-G2) (CBMAB-A6091-LY)

Name: Mouse Anti-NQO2 Recombinant Antibody (3E8-G2)
SKU: CBMAB-A6091-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3E8-G2

Application

WB, ELISA

Immunogen

NQO2 (AAH06096.1, 1 a.a. ~ 231 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

N-Ribosyldihydronicotinamide:Quinone Reductase 2

Entrez Gene ID

4835

UniProt ID

P16083

Alternative Names

DHQV; DIA6; NMOR2; QR2

Function

The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

Biological Process

Quinone catabolic processManual Assertion Based On ExperimentIDA:CAFA

Cellular Location

Cytoplasm

Janda, E., Boutin, J. A., De Lorenzo, C., & Arbitrio, M. (2024). Polymorphisms and Pharmacogenomics of NQO2: The Past and the Future. Genes, 15(1), 87.

Rashid, M. H., Babu, D., & Siraki, A. G. (2021). Interactions of the antioxidant enzymes NAD (P) H: Quinone oxidoreductase 1 (NQO1) and NRH: Quinone oxidoreductase 2 (NQO2) with pharmacological agents, endogenous biochemicals and environmental contaminants. Chemico-Biological Interactions, 345, 109574.

Schepers, A. G., Shan, J., Cox, A. G., Huang, A., Evans, H., Walesky, C., ... & Bhatia, S. N. (2021). Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function. ACS Chemical Biology, 16(9), 1770-1778.

Janda, E., Nepveu, F., Calamini, B., Ferry, G., & Boutin, J. A. (2020). Molecular pharmacology of NRH: quinone oxidoreductase 2: A detoxifying enzyme acting as an undercover toxifying enzyme. Molecular Pharmacology, 98(5), 620-633.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

NQO2 Matched Antibody Pair (815) (CAT#: APMAB-815LY)

NQO2 Matched Antibody Pair (816) (CAT#: APMAB-816LY)

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NQO2 Matched Antibody Pair (815) (CAT#: APMAB-815LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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