NRN1

This gene encodes a member expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.

Neuritin 1

Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.

Neuron projection extensionManual Assertion Based On ExperimentIBA:GO_Central

Cell membrane
Cell junction, synapse