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NRN1

This gene encodes a member expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.

Full Name

Neuritin 1

Function

Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.

Biological Process

Neuron projection extensionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane
Cell junction, synapse

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Anti-NRN1 antibodies

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Mouse Anti-NRN1 Recombinant Antibody (CBWJN-0670) (CBMAB-N3608-WJ)

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Target: NRN1

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: CBWJN-0670

Application*: WB, N

Mouse Anti-NRN1 Recombinant Antibody (CBWJN-0224) (CBMAB-N3605-WJ)

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Target: NRN1

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: CBWJN-0224

Application*: WB

Human Recombinant NRN1 protein, His Tag (V2LY-0526-LY5761)

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Target: NRN1

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 1-115

Tag: His Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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