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NT5C3B

Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).

Full Name

5'-Nucleotidase, Cytosolic IIIB

Function

Specifically hydrolyzes 7-methylguanosine monophosphate (m7GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684).
The specific activity for m7GMP may protect cells against undesired salvage of m7GMP and its incorporation into nucleic acids (PubMed:23223233).
Also has weak activity for CMP (PubMed:23223233, PubMed:24603684).
UMP and purine nucleotides are poor substrates (PubMed:23223233).

Biological Process

Exonucleolytic catabolism of deadenylated mRNATAS:Reactome
Nucleotide metabolic processIEA:UniProtKB-KW

Cellular Location

Cytoplasm

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Anti-NT5C3B antibodies

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Mouse Anti-NT5C3B Recombinant Antibody (D-8) (CBMAB-N3681-WJ)

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Target: NT5C3B

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: D-8

Application*: WB, IP, IF, E

Mouse Anti-NT5C3B Recombinant Antibody (C-6) (CBMAB-N3680-WJ)

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Target: NT5C3B

Host: Mouse

Specificity: Human

Clone: C-6

Application*: WB, IP, IF, E

Mouse Anti-NT5C3B Recombinant Antibody (A-7) (CBMAB-N3679-WJ)

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Target: NT5C3B

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: A-7

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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