NT5C3B

Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).
Full Name
5'-Nucleotidase, Cytosolic IIIB
Function
Specifically hydrolyzes 7-methylguanosine monophosphate (m7GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684).
The specific activity for m7GMP may protect cells against undesired salvage of m7GMP and its incorporation into nucleic acids (PubMed:23223233).
Also has weak activity for CMP (PubMed:23223233, PubMed:24603684).
UMP and purine nucleotides are poor substrates (PubMed:23223233).
Biological Process
Exonucleolytic catabolism of deadenylated mRNATAS:Reactome
Nucleotide metabolic processIEA:UniProtKB-KW
Cellular Location
Cytoplasm
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Anti-NT5C3B antibodies

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Mouse Anti-NT5C3B Recombinant Antibody (D-8) (CBMAB-N3681-WJ)

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Target: NT5C3B
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: D-8
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-NT5C3B Recombinant Antibody (C-6) (CBMAB-N3680-WJ)

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Target: NT5C3B
Host: Mouse
Specificity: Human
Clone: C-6
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-NT5C3B Recombinant Antibody (A-7) (CBMAB-N3679-WJ)

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Target: NT5C3B
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: A-7
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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