Mouse Anti-NT5C3B Recombinant Antibody (C-6) (CBMAB-N3680-WJ)

Name: Mouse Anti-NT5C3B Recombinant Antibody (C-6)
SKU: CBMAB-N3680-WJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

C-6

Application

WB, IP, IF, ELISA

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

5'-Nucleotidase, Cytosolic IIIB

Introduction

Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).

Entrez Gene ID

115024

UniProt ID

Q969T7

Alternative Names

5'-Nucleotidase, Cytosolic IIIB; 5-Nucleotidase, Cytosolic IIIB; Cytosolic 5-Nucleotidase III-Like Protein; 5-Nucleotidase, Cytosolic III-Like; N(7)-Methylguanylate 5-Phosphatase; 7-Methylguanosine Nucleotidase; Cytosolic 5-Nucleotidase 3B;

Function

Specifically hydrolyzes 7-methylguanosine monophosphate (m7GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684).
The specific activity for m7GMP may protect cells against undesired salvage of m7GMP and its incorporation into nucleic acids (PubMed:23223233).
Also has weak activity for CMP (PubMed:23223233, PubMed:24603684).
UMP and purine nucleotides are poor substrates (PubMed:23223233).

Biological Process

Exonucleolytic catabolism of deadenylated mRNATAS:Reactome
Nucleotide metabolic processIEA:UniProtKB-KW

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-NT5C3B Recombinant Antibody (A-7) (CAT#: CBMAB-N3679-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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