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Mouse Anti-NT5C3B Recombinant Antibody (A-7) (CBMAB-N3679-WJ)

This product is a Mouse antibody that recognizes NT5C3B. The antibody A-7 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all NT5C3B antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
A-7
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
5'-Nucleotidase, Cytosolic IIIB
Introduction
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).
Entrez Gene ID
Human115024
Mouse68106
Rat360629
UniProt ID
HumanQ969T7
MouseQ3UFY7
RatQ6AYP7
Alternative Names
5'-Nucleotidase, Cytosolic IIIB; 5-Nucleotidase, Cytosolic IIIB; Cytosolic 5-Nucleotidase III-Like Protein; 5-Nucleotidase, Cytosolic III-Like; N(7)-Methylguanylate 5-Phosphatase; 7-Methylguanosine Nucleotidase; Cytosolic 5-Nucleotidase 3B;
Function
Specifically hydrolyzes 7-methylguanosine monophosphate (m7GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684).
The specific activity for m7GMP may protect cells against undesired salvage of m7GMP and its incorporation into nucleic acids (PubMed:23223233).
Also has weak activity for CMP (PubMed:23223233, PubMed:24603684).
UMP and purine nucleotides are poor substrates (PubMed:23223233).
Biological Process
Exonucleolytic catabolism of deadenylated mRNATAS:Reactome
Nucleotide metabolic processIEA:UniProtKB-KW
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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