NTN4

This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Full Name
Netrin 4
Function
May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.
Biological Process
Animal organ morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Basement membrane assemblyManual Assertion Based On ExperimentIBA:GO_Central
Cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Neuron remodelingIEA:Ensembl
Regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signalingIEA:Ensembl
Substrate adhesion-dependent cell spreadingManual Assertion Based On ExperimentIBA:GO_Central
Tissue developmentManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted, extracellular space, extracellular matrix, basement membrane
Major component.
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Anti-NTN4 antibodies

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Mouse Ntn4 ELISA Kit (V2LY-0626-LY2738)

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Target: Ntn4
Sensitivity: 0.0091 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Human NTN4 ELISA Kit (V2LY-0626-LY1549)

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Target: NTN4
Sensitivity: 0.044 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Mouse Anti-NTN4 Recombinant Antibody (CBWJN-0737) (CBMAB-N3764-WJ)

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Target: NTN4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0737
Application*: E, IP, WB
Datasheet SDS

Mouse Anti-NTN4 Recombinant Antibody (CBWJN-0222) (CBMAB-N3761-WJ)

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Target: NTN4
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBWJN-0222
Application*: WB
Datasheet SDS

Rat Anti-NTN4 Recombinant Antibody (CBWJN-1575) (CBMAB-N3760-WJ)

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Target: NTN4
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBWJN-1575
Application*: WB
Datasheet SDS

Mouse Anti-NTN4 Recombinant Antibody (CBWJN-0734) (CBMAB-N0552-WJ)

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Target: NTN4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJN-0734
Application*: E, WB
Datasheet SDS

Mouse Anti-NTN4 Recombinant Antibody (CBWJN-1037) (CBMAB-N0551-WJ)

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Target: NTN4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJN-1037
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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