ONECUT2
This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
Full Name
ONECUT2
Function
Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.
Biological Process
Animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Cell fate commitmentIEA:Ensembl
Cilium assemblyIEA:Ensembl
Endocrine pancreas developmentIEA:Ensembl
Epithelial cell developmentIEA:Ensembl
Liver developmentIEA:Ensembl
Negative regulation of transforming growth factor beta receptor signaling pathwayIEA:Ensembl
Peripheral nervous system neuron developmentIEA:Ensembl
Positive regulation of cell migrationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of cell-matrix adhesionIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cell fate commitmentIEA:Ensembl
Cilium assemblyIEA:Ensembl
Endocrine pancreas developmentIEA:Ensembl
Epithelial cell developmentIEA:Ensembl
Liver developmentIEA:Ensembl
Negative regulation of transforming growth factor beta receptor signaling pathwayIEA:Ensembl
Peripheral nervous system neuron developmentIEA:Ensembl
Positive regulation of cell migrationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of cell-matrix adhesionIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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Anti-ONECUT2 antibodies
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Target: ONECUT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXO-0389
Application*: WB, IC
Target: ONECUT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1A1
Application*: IP, M
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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