PCF11

Pcf11 binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage.
Full Name
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
Function
Component of pre-mRNA cleavage complex II.
Biological Process
mRNA cleavage1 PublicationNAS:UniProtKB
mRNA polyadenylationManual Assertion Based On ExperimentIBA:GO_Central
Termination of RNA polymerase II transcriptionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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Anti-PCF11 antibodies

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Target: PCF11
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: C-9
Application*: WB, IP, IF, E
Target: PCF11
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3G4
Application*: E, WB, P
Target: PCF11
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A-7
Application*: WB, IP, IF, E
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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