PCF11

Pcf11 binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage.

Full Name

PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)

Function

Component of pre-mRNA cleavage complex II.

Biological Process

mRNA cleavage1 PublicationNAS:UniProtKB
mRNA polyadenylationManual Assertion Based On ExperimentIBA:GO_Central
Termination of RNA polymerase II transcriptionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Anti-PCF11 antibodies

Mouse Anti-Pcf11 Recombinant Antibody (C-9) (CBMAB-P1038-YC)

Datasheet

SDS

Target: PCF11

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: C-9

Application*: WB, IP, IF, E

Mouse Anti-Pcf11 Recombinant Antibody (A-7) (CBMAB-P1037-YC)

Datasheet

SDS

Target: PCF11

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: A-7

Application*: WB, IP, IF, E

Mouse Anti-PCF11 Recombinant Antibody (3G4) (CBMAB-P1036-YC)

Datasheet

SDS

Target: PCF11

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3G4

Application*: E, WB, P

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)