PDCD1LG2

PDCD1LG2 (Programmed Cell Death 1 Ligand 2) is a Protein Coding gene. Diseases associated with PDCD1LG2 include Cysticercosis and Myasthenic Syndrome, Congenital, 14. Among its related pathways are Innate Immune System and NF-kappaB Signaling. An important paralog of this gene is CD274.
Full Name
Programmed Cell Death 1 Ligand 2
Alternative Names
Programmed Cell Death 1 Ligand 2; B7 Dendritic Cell Molecule; Programmed Death Ligand 2; Butyrophilin B7-DC; PDCD1 Ligand 2; PDCD1L2; B7-DC; CD273; PD-L2;
Function
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Biological Process
Adaptive immune responseIEA:UniProtKB-KW
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular response to lipopolysaccharideManual Assertion Based On ExperimentIBA:GO_Central
Immune responseManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of activated T cell proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of interferon-gamma productionManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of interleukin-10 productionManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of T cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of T cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
T cell costimulationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Isoform 3
Secreted
Isoform 2
Endomembrane system
Isoform 1
Cell membrane
Topology
Extracellular: 20-220
Helical: 221-241
Cytoplasmic: 242-273
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Anti-PDCD1LG2 antibodies

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Mouse Anti-PDCD1LG2 Recombinant Antibody (MIH14) (CBMAB-P1151-YC)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MIH14
Application*: F, C
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (AG148) (V2LY-0524-LY169)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: AG148
Application*: B, F
Functional Assay
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (AG147) (V2LY-0524-LY161)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: AG147
Application*: F, C, IP, WB
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (A1403) (CBMAB-AP11410LY)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: A1403
Application*: FC, IHC, IP, WB
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (3E9) (CBMAB-A6497-LY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3E9
Application*: WB, E
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (6E4) (CBMAB-A6495-LY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6E4
Application*: E, E
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (2E2) (CBMAB-A6494-LY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E2
Application*: WB, E
Datasheet SDS

Recombinant Mouse Anti-PDCD1LG2 Recombinant Antibody (Z64P2D3) (CBMAB-XB0915-YC)

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Target: PDCD1LG2
Host: Mouse
Specificity: Human
Clone: Z64P2D3
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (Z64P2D3/H4) (CBMAB-P1154-YC)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: Z64P2D3/H4
Application*: WB, E, IH
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (TY25) (CBMAB-P1153-YC)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: TY25
Application*: F, IH, C
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (MIH5) (CBMAB-P1152-YC)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG2a, λ
Specificity: Mouse
Clone: MIH5
Application*: F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (ANC8D12) (CBMAB-P1150-YC)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: ANC8D12
Application*: B, E, F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (7C1) (CBMAB-P1148-YC)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 7C1
Application*: E, WB, P, IC, IF, F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (4E10) (CBMAB-P1147-YC)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E10
Application*: E, WB, P, IC, IF, F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (10B6) (CBMAB-P1144-YC)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 10B6
Application*: WB, F, IH, P
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (54-1) (CBMAB-C7166-LY)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 54-1
Application*: F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (176611) (CBMAB-C3428-LY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 176611
Application*: F, C, WB
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (24F.10C12) (CBMAB-C0733-LY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 24F.10C12
Application*: F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (10B1186) (CBMAB-C0138-LY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B1186
Application*: F, IH
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (CBT4273) (V2LY-0625-LY1605)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT4273
Application*: F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (CBT4161) (V2LY-0625-LY1604)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT4161
Application*: WB, IC, F
Datasheet SDS

PDCD1LG2 Matched Antibody Pair (852) (APMAB-852LY)

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Target: PDCD1LG2
Specificity: Human
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (CBWJC-2358) (CBMAB-C3305WJ)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJC-2358
Application*: F, E, B
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (CBXC-1462) (CBMAB-C3503-CQ)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXC-1462
Application*: F, IP, WB
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (CBXC-1386) (CBMAB-C2613-CQ)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-1386
Application*: F, IH, IP
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (MIH18) (CBMAB-C1796-CQ)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MIH18
Application*: F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (CBFYC-3024) (CBMAB-C3101-FY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-3024
Application*: F
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (CBFYC-3023) (CBMAB-C3100-FY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-3023
Application*: F, IH
Datasheet SDS

Mouse Anti-PDCD1LG2 Recombinant Antibody (CBFYC-3022) (CBMAB-C3099-FY)

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Target: PDCD1LG2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-3022
Application*: F, IH, WB
Datasheet SDS

Rat Anti-PDCD1LG2 Recombinant Antibody (CBFYC-0241) (CBMAB-C0270-FY)

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Target: PDCD1LG2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBFYC-0241
Application*: F
Datasheet SDS

Rabbit Anti-PDCD1LG2 Recombinant Antibody (CBYY-1146) (CBMAB-1150-YY)

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Target: PDCD1LG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBYY-1146
Application*: WB
Datasheet SDS

Rabbit Anti-PDCD1LG2 Recombinant Antibody (CBYY-1145) (CBMAB-1149-YY)

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Target: PDCD1LG2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-1145
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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