PHOSPHO1

PHOSPHO1 has biased expression in testis (RPKM 17.3), bone marrow (RPKM 8.3) and 3 other tissues.
Full Name
Phosphoethanolamine/Phosphocholine Phosphatase
Function
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho) (PubMed:15175005).
Involved in the generation of inorganic phosphate for bone mineralization (By similarity).
Acts in a non-redundant manner with PHOSPHO1 in skeletal mineralization: while PHOSPHO1 mediates the initiation of hydroxyapatite crystallization in the matrix vesicles (MVs), ALPL/TNAP catalyzes the spread of hydroxyapatite crystallization in the extracellular matrix (By similarity).
Biological Process
Bone mineralizationISS:UniProtKB
Bone mineralization involved in bone maturationManual Assertion Based On ExperimentIBA:GO_Central
Endochondral ossificationIEA:Ensembl
Regulation of bone mineralizationIEA:UniProtKB-KW
Cellular Location
Extracellular vesicle
Localizes to special class of extracellular vesicles, named matrix vesicles (MVs), which are released by osteogenic cells.
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Anti-PHOSPHO1 antibodies

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Human Anti-PHOSPHO1 Recombinant Antibody (CBYC-P354) (CBMAB-P1699-YC)

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Target: PHOSPHO1
Host: Human
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBYC-P354
Application*: E, WB
Datasheet SDS

Mouse Anti-PHOSPHO1 Recombinant Antibody (4B2) (CBMAB-P1698-YC)

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Target: PHOSPHO1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4B2
Application*: E, WB
Datasheet SDS

Mouse Anti-PHOSPHO1 Recombinant Antibody (1A11) (CBMAB-P1697-YC)

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Target: PHOSPHO1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A11
Application*: E, WB
Datasheet SDS

Human Recombinant PHOSPHO1 protein, His Tag (V2LY-0526-LY6145)

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Target: PHOSPHO1
Expressed Host: E. coli
Sequence: Amino Acid: 1-267
Tag: His Tag
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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