PLA2G12A

Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM

Full Name

phospholipase A2, group XIIA

Function

PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.

Biological Process

Arachidonic acid secretionIEA:InterPro
Lipid catabolic processIEA:UniProtKB-KW
Phospholipid metabolic processIEA:InterPro

Cellular Location

Secreted
Cytoplasm

Anti-PLA2G12A antibodies

Mouse Anti-PLA2G12A Recombinant Antibody (CBLG1-3240) (CBMAB-G6460-LY)

Datasheet

SDS

Target: PLA2G12A

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBLG1-3240

Application*: WB

Mouse Anti-PLA2G12A Recombinant Antibody (7C7C9) (CBMAB-P1981-YC)

Datasheet

SDS

Target: PLA2G12A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 7C7C9

Application*: WB, F, E, MC

Mouse Anti-PLA2G12A Recombinant Antibody (3H2C11) (CBMAB-P1980-YC)

Datasheet

SDS

Target: PLA2G12A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3H2C11

Application*: WB, P, F

Mouse Anti-PLA2G12A Recombinant Antibody (1D11) (CBMAB-P1979-YC)

Datasheet

SDS

Target: PLA2G12A

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1D11

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)