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POU3F1

POU3F1 may act as a transcriptional regulator of gene expression during Schwann cell differentiation and myelination.

Full Name

POU domain, class 3, transcription factor 1

Function

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') (By similarity).
Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity).
Acts as a transcriptional repressor of myelin-specific genes (By similarity).

Biological Process

Axon ensheathmentManual Assertion Based On ExperimentTAS:ProtInc
Forebrain developmentIEA:Ensembl
Keratinocyte differentiationIEA:Ensembl
Myelination in peripheral nervous systemIEA:Ensembl
Positive regulation of gene expressionISS:UniProtKB
Positive regulation of transcription, DNA-templatedISS:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Anti-POU3F1 antibodies

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Rabbit Anti-POU3F1 Recombinant Antibody (EP5421) (CBMAB-1934-YC)

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Target: POU3F1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: EP5421

Application*: WB

Mouse Anti-POU3F1 Recombinant Antibody (CBXO-0315) (CBMAB-O0293-CQ)

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Target: POU3F1

Host: Mouse

Specificity: Human

Clone: CBXO-0315

Application*: WB, IP, IF, P, E

Mouse Anti-POU3F1 Recombinant Antibody (CBXO-0312) (CBMAB-O0292-CQ)

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Target: POU3F1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXO-0312

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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